"I have always endeavoured to be guided by reason, and not by prejudice."

"The path of discovery is not a smooth one; it is often beset with difficulties and discouragements."

"You see by the papers how I'm annoyed by a set of blockheads who write about the imperfection of the cowpox, as a vaccine, without any knowledge scarcely of its phenomena."

"It seems to be the determination of some of the jealous members of the ****** (R. *** Soc. y), not to suffer the Institution to sink, but on the / Other hand to master up a force, & support it with al…"

"I have often been accused of being too sanguine in my expectations; but time will show whether I am right or wrong."